St. George's, Grenada:Captain Shakib-al-Hasan reached 5-70 as Bangladesh closed in on its first overseas series win after West Indies was bowled out for 209 on a rain-hit fourth day of the second Test.
Bangladesh, set a victory target of 215, safely negotiated six overs before lunch as they reached 17-0.
Tamim Iqbal was unbeaten on 12 while his opening partner Imrul Kayes was 4 not out.
Bangladesh is seeking a series sweep following its victory in the opening test in St. Vincent a week ago.
Persistent morning rain delayed the start of day four by more than two hours, but Bangladesh struck early once play resumed.
David Bernard Jr., who was 61 not out overnight, launched a six over straight long off but added just eight runs. The elegant right-hander was neatly stumped by wicket-keeper Mushfiqur Rahim as he missed an on-drive at a big turner from Enamul. The Jamaican hit six fours and two sixes in his topscore of 69 off 76 balls.
Tailender Tino Best also lofted a six but fell two balls later as he gloved a paddle sweep at Shakib, who collected his fifth five-wicket haul in his 14th Test.
Kemar Roach finished on one not out.
Enamul claimed 3-48 to support his skipper.
The West Indies surprisingly opted not to use Roach with the new ball despite the lithe fast bowler collecting 6-48 in the first innings.
Instead, Best and Bernard shared the first six overs without success.
Tamim crunched one pulled four as he and Imrul comfortably saw Bangladesh to the break.