Top-ranked Serena Williams is seeded No. 1 as she seeks her third straight U.S. Open title. (Djokovic, Federer top two seeds in US Open)
The U.S. Tennis Association followed this week's WTA rankings in announcing the seedings on Wednesday.
French Open runner-up Simona Halep is seeded second after reaching a career-best ranking this month. She has never advanced past the fourth round at the U.S. Open.